Synthesis of bis(indole) alkaloids from Arundo donax: the ynindole Diels-Alder reaction, conformational chirality, and absolute stereochemistry.
نویسندگان
چکیده
Bis(indole) alkaloids from Arundo donax were synthesized using the first ynindole Diels-Alder reaction. The alkaloids are chiral, having stable enantiomeric conformations with half-lives of racemization of t1/2 = 4150-25100 seconds at room temperature. Their absolute stereochemistry was determined using the exciton chirality method.
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ورودعنوان ژورنال:
- Angewandte Chemie
دوره 53 44 شماره
صفحات -
تاریخ انتشار 2014